Science-Backed
Explore the science-backed compounds that make Aftershock the most effective preworkout on the market
27 of 27 ingredients
L-Citrulline is a non-essential amino acid that plays a crucial role in the urea cycle, helping to remove ammonia from the body. It's converted to L-arginine in the kidneys, leading to increased nitric oxide production.
Lion's Mane (Hericium erinaceus) is a mushroom frequently discussed in nootropic and focus-oriented supplements. Research interest is driven mainly by hericenones and erinacines, but real-world expectations should stay measured.
Caffeine is the world's most widely consumed psychoactive substance. It works primarily by blocking adenosine receptors in the brain, preventing fatigue and increasing alertness.
L-Tyrosine is a non-essential amino acid that serves as a precursor to important neurotransmitters including dopamine, norepinephrine, and epinephrine. It's particularly beneficial during stress.
Creatine monohydrate is one of the most researched and effective supplements for increasing muscle mass, strength, and exercise performance. It helps regenerate ATP (adenosine triphosphate) in muscle cells.
Betaine anhydrous (trimethylglycine) is an amino acid derivative that supports methylation processes, muscle growth, and exercise performance. It acts as an osmolyte and methyl donor.
Glycerol is a hyperhydrating agent that enhances fluid retention and blood volume. It helps maintain hydration during intense exercise and improves endurance performance.
Malic acid is a key intermediate in the Krebs cycle (citric acid cycle), essential for cellular energy production. It helps reduce muscle fatigue and supports ATP regeneration.
Ginseng is a powerful adaptogenic herb that has been used for centuries to enhance energy, reduce stress, and improve physical and mental performance. It contains active compounds called ginsenosides.
Rhodiola rosea is an adaptogenic herb commonly discussed in the context of fatigue, stress load, and mental performance. Interest usually focuses on rosavins and salidroside, but practical expectations should still stay realistic.
L-Theanine is an amino acid found mainly in tea leaves and is popular in supplements built around calmer focus. It is especially common next to caffeine, where users want a smoother stimulation profile.
Himalayan pink salt is a natural source of essential electrolytes including sodium, potassium, magnesium, and calcium. It supports hydration, muscle function, and electrolyte balance.
Vitamin B12 is essential for energy metabolism, nerve function, DNA synthesis, and red blood cell formation. Methylcobalamin is the most bioactive form.
Vitamin B3 (niacinamide) is essential for energy metabolism, cellular repair, and cardiovascular health. It supports over 400 enzymatic reactions in the body.
Vitamin B6 is involved in amino acid metabolism and many everyday physiological processes. In supplements it often appears as a supportive micronutrient rather than as the main reason to buy the formula.
Potassium chloride is an essential electrolyte that supports muscle function, nerve transmission, and cardiovascular health. It helps maintain proper fluid balance.
Glycine is the smallest amino acid and is usually discussed in relation to collagen, sleep quality, and recovery. It is simple, familiar, and often used in evening-oriented supplement conversations.
Citicoline (CDP-Choline) is a powerful nootropic that supports brain health, memory, and cognitive function. It provides choline and enhances phospholipid synthesis.
Huperzine A is a natural compound extracted from the Chinese club moss Huperzia serrata. It acts as an acetylcholinesterase inhibitor, meaning it slows the breakdown of acetylcholine in the brain. It has attracted research interest for memory and learning, though most clinical work has been done in specific populations and the broader applicability is still being studied.
Racetams are a family of synthetic compounds sharing a pyrrolidone nucleus structure. They include piracetam, aniracetam, oxiracetam, and others. Piracetam was the first compound in this class, synthesized in the 1960s, and the term "nootropic" was originally coined to describe it. Their mechanisms are not fully understood, and regulatory status varies by country.
B-complex refers to the group of eight essential B vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). They play interconnected roles in energy metabolism, nervous system function, and red blood cell formation. Deficiency in any single B vitamin can disrupt the function of others.
GABA is the primary inhibitory neurotransmitter in the central nervous system. It reduces neuronal excitability and plays a key role in regulating anxiety, muscle tone, and sleep. While the body produces GABA naturally, supplemental GABA is widely sold. The central question around oral GABA supplementation is whether it meaningfully crosses the blood-brain barrier, and this remains debated.
Bacopa monnieri, also known as Brahmi, is an herb used in traditional Ayurvedic medicine for centuries. Modern research has focused on its bacosides (active compounds) and their effects on memory and cognitive function. It tends to show results over weeks rather than acutely, and the evidence base, while promising, is still developing.
Iron is an essential mineral involved in oxygen transport, energy production, and immune function. It is a component of hemoglobin in red blood cells and myoglobin in muscle tissue. Iron deficiency is the most common nutritional deficiency worldwide, particularly affecting women of reproductive age, athletes, and vegetarians. Supplementation is clearly beneficial for deficiency but should not be taken without reason, as excess iron can be harmful.
Copper is an essential trace mineral that serves as a cofactor for numerous enzymes involved in energy production, iron metabolism, connective tissue formation, and antioxidant defense. The body requires only small amounts, and copper deficiency is relatively rare in well-nourished populations. However, it can occur in individuals with malabsorption conditions or excessive zinc supplementation.
Magnesium is the fourth most abundant mineral in the body and a cofactor in over 300 enzymatic reactions. It is involved in energy production, muscle and nerve function, blood sugar regulation, and bone health. Subclinical magnesium deficiency is thought to be widespread in modern diets, particularly due to soil depletion and processed food consumption. Different forms of magnesium have different bioavailability and clinical applications.
Sodium is an essential electrolyte that regulates fluid balance, blood pressure, and nerve impulse transmission. While excess sodium intake is a well-known health concern in the general population, adequate sodium is critical during exercise and in hot environments. Athletes and individuals on low-carb diets may actually need more sodium than the general guidelines suggest. The key is context-dependent intake rather than blanket restriction.