Alpha GPC
Alpha GPC (L-Alpha glycerylphosphorylcholine) is a highly bioavailable choline compound that crosses the blood-brain barrier. It's one of the most effective sources of choline for cognitive enhancement.
Key Benefits
Acetylcholine Production
Increases brain acetylcholine levels for better memory and learning.
Growth Hormone Support
May increase growth hormone production, especially when combined with exercise.
Power Output
Enhances power production and strength in athletes.
Brain Protection
Provides neuroprotective benefits and supports brain health.
How It Works
Alpha GPC rapidly delivers choline to the brain where it's converted to acetylcholine, a neurotransmitter essential for memory, learning, and muscle contraction. It also supports phospholipid synthesis.
Scientific Research
The effect of alpha-GPC on growth hormone, fat oxidation and force production
Journal of the International Society of Sports Nutrition • 2021
Alpha-GPC increased growth hormone levels and enhanced power output.
Read StudyCognitive improvement in mild to moderate Alzheimer's dementia
Clinical Therapeutics • 2003
Alpha-GPC showed significant cognitive improvements in dementia patients.
Read StudyFrequently Asked Questions
What is the best time to take Alpha GPC?
For cognitive performance, take Alpha GPC 30-60 minutes before the activity requiring mental focus. For training, take it as part of your pre-workout stack. Some users find morning dosing beneficial for all-day cognitive support. Avoid late evening use as it may increase alertness.
Is Alpha GPC better than regular choline supplements?
Alpha GPC has the highest bioavailability among choline sources because it crosses the blood-brain barrier efficiently. Regular choline bitartrate is cheaper but less effective for cognitive enhancement. CDP-Choline (Citicoline) is another premium form with similar benefits.
Can Alpha GPC help with athletic performance?
Yes. Research shows Alpha GPC can increase growth hormone secretion and improve power output. A 2021 study in JISSN found that 600mg Alpha GPC before training enhanced lower body force production. It also supports the mind-muscle connection through increased acetylcholine availability.
Safety Information
Possible Side Effects
- Headache
- Dizziness
- Heartburn
- Confusion (at high doses)
Drug Interactions
- Scopolamine
- Anticholinergic medications
Contraindications
- None well-established
Dosage Information
Recommended Daily Dose
300-600mg per day
Range
300-1200mg
Timing
Morning or before mentally demanding tasks
Can be taken with or without food. Athletic performance doses may be higher.
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